MESvantage
The platform

50+ validated modules. One platform.

Six interconnected domains covering the full medical-device manufacturing lifecycle — from incoming inspection to executive intelligence.

Domain 01 · Quality

Quality, end to end. ISO 13485 by design.

A complete quality management suite covering incoming goods, in-process inspection, FAI, SPC, NCR/CAPA workflows, and OEM-facing customer portals. Every record is electronically signed and version-locked under 21 CFR Part 11.

  • First Article Inspection (FAI)
  • First Pass Yield (FPY) tracking
  • Statistical Process Control (SPC)
  • Device History Record (DHR)
  • Incoming Inspection workflow
  • Non-Conformance Reports (NCR)
  • Corrective Action (CAPA)
  • Customer Quality Portal
  • Hold & quarantine management
  • Quality KPI dashboards
  • Out-of-tolerance alerting
  • Root-cause analysis tooling
app.mesvantage.com / quality / dashboard

Quality Operations

Live · Sample data · 7 day rolling

● Synced ISO 13485
FPY
99.2%
+0.3%
Open NCRs
3
−2 wk
Open CAPAs
7
4 on track
Lots on hold
1
awaiting MRB
Cpk avg
1.87
goal 1.67
SPC — PT-2049-B · Feature D2 (Ø 12.7 ±0.05)
Last 32 measurements · Cpk 1.87 · Within control
● In control
USL 12.75 LSL 12.65 12.70
Inspection queue · 4 pending
#TypePartOperationInspectorStatus
INS-4892 FAI PT-2103-A OP-030 Patel R. ● In progress
INS-4891 In-process PT-2049-B OP-020 Doyle M. ● Pass
INS-4890 Final PT-2210-C OP-070 Walsh F. ● Pass
INS-4889 Incoming RM-7732 Doyle M. ● Pending
Domain 02 · Production

Real-time floor intelligence. No manual entry.

Live OEE direct from machine telemetry. Closed-loop scheduling that absorbs unplanned downtime in real time. In-process documentation that operators actually use because it's on the work order, not on the shared drive.

  • OEE — live per machine and fleet
  • Production scheduling (closed-loop)
  • In-Process Documentation (IPD)
  • Standard Times & variance analysis
  • Operator graduation & release
  • Work order execution tracking
  • Setup time tracking
  • Downtime root-cause coding
  • Shift handover briefings
  • Throughput vs. takt time
  • Cell load balancing
  • Live escalation routing
app.mesvantage.com / scheduling

Production schedule · Today

Updated 14:06 · 4 cells · 3 shifts

06:0008:0010:0012:0014:0016:0018:0020:0022:00
Cell 01
PT-2049-B · 320u
PT-2103-A · 180u
Setup
Cell 02
PT-2049-B · 290u
PT-2049-B · 240u
PT-2210-C · 210u
Cell 03
PT-2049-B · 200u
Down
Setup
PT-2103-A · 180u
Cell 04
PT-2210-C · 410u
PT-2210-C · 290u
PT-2049-B · 90u
CMM Bay
FAI
IP
IP
IP
Final
IP
OEE breakdown — fleet, today
Loaded time 100%
Availability 94% 94%
× Performance 89% 84%
× Quality 99.2% 83%
OEE = 78.4% 78%
Standard time variance — by part
PT-2049-B
+12%
PT-2103-A
−3%
PT-2210-C
+1%
PT-2188-D
−7%
PT-2099-E
+24%
Domain 03 · Metrology

CMM data, parsed automatically.

AI-powered ingestion for Renishaw, Hexagon, and Zeiss output. The platform reads the report, extracts every feature, links it back to the part drawing tolerance, flags out-of-tolerance, and writes the result to the DHR — without an inspector touching a keyboard.

  • CMM result ingestion (auto)
  • Renishaw / Hexagon / Zeiss support
  • AI feature-to-tolerance mapping
  • Calibration management
  • Out-of-tolerance alerting
  • GD&T attribute parsing
  • Instrument type classification
  • Operator-readable PDF reports
  • Drift detection over lots
  • Auto-link to part revision
app.mesvantage.com / metrology / report / HX-2026-1184
CMM Report

HX-2026-1184 · Hexagon Global S

Part PT-2049-B rev D · Op 020 · 18 features · auto-parsed in 1.2s

● 18/18 in tolerance AI-parsed
Feature Type Nominal Actual Dev Tol Status
D1 Diameter 12.700 12.703 +0.003 ±0.050
D2 Diameter 8.500 8.498 −0.002 ±0.030
L1 Length 45.000 45.012 +0.012 ±0.100
L2 Length 22.500 22.498 −0.002 ±0.050
P1 Position 0.000 0.018 +0.018 ⌀0.050 MMC
P2 Position 0.000 0.012 +0.012 ⌀0.050 MMC
F1 Flatness 0.000 0.008 +0.008 0.020
CY1 Cylindricity 0.000 0.012 +0.012 0.030
Auto-linked to DHR · SN-A4729-00184 · Lot LT-2026-Q2-018 Parsed by MESvantage v3.4 · model cmm-parse-v9
Domain 04 · Training

Training enforced at the point of work.

Operators only see operations they're trained for. Trainer/trainee workflows are built into the work order, not bolted on as a checklist. Cert expiry triggers automatic graduation review.

  • Training enforcement at WO start
  • Trainer/trainee context tracking
  • Operator scope by part / op
  • Qualio QMS bidirectional sync
  • Cert expiry alerts
  • Graduation workflow
  • Training gap analytics
  • Skills matrix by cell
  • Re-training trigger rules
  • Audit-ready training history
app.mesvantage.com / training / skills-matrix

Skills Matrix · Cell 01–04

9 operators · 8 part programs · live from Qualio

● Certified ▲ Trainee ✕ Expired
Operator PT-2049-BPT-2103-APT-2210-CPT-2188-DPT-2099-EPT-2317-FPT-2401-GCMM Ops
Smith K.
Jones K.
Patel R.
Doyle M.
·
Walsh F.
O'Brien S.
·
Lynch J.
Ryan P.
·
·
Murphy A.
·
⚠ Cert expired — Lynch J. · PT-2210-C · expired 2 days ago. Re-cert WO drafted.
▲ Trainee active — Murphy A. on PT-2049-B with trainer Patel R. · 3 hrs logged.
Domain 05 · Intelligence

From shop floor to CEO. One pane of glass.

Live executive intelligence aggregated across operations, finance, supply chain, and quality. Powered by a purpose-built LLM that reads your ERP, your QMS, and your floor in real time.

  • CEO Intelligence Dashboard
  • AI Executive Agent (LLM)
  • Energy & sustainability intel
  • Machine intelligence (predictive)
  • Customer-facing portals
  • Power BI bidirectional
  • Ops intelligence stream
  • Continuous improvement tracker
  • BD & pipeline intel
  • Competitive intel feed
  • Energy ECM live data
  • Anomaly detection (auto)
app.mesvantage.com / ceo
Executive Intelligence

Operations Pulse · May 2026

● All systems live
Output MTD
38,420
units · 102% plan
On-time delivery
97.4%
+2.1pp MoM
COGS variance
−1.8%
vs. budget
NCR rate
0.42%
−0.08pp MoM
Output trend · last 30 days
AI insights
Up · PT-2049-B yield trending +2.4pp; expect to clear backlog by Friday.
Watch · Cell 03 thermal drift recurring weekly. Recommend tool study.
Up · Energy: solar offset hit 41% peak last Sun. EUR 2.4k saved MTD.
Customer portal: 3 OEMs viewed lot release packets in last 24h.
Domain 06 · Platform

Compliance-grade foundations.

Every record signed, hashed, and audit-trailed. Every action role-gated. Every customer in their own isolated environment. The platform is the validation evidence — not a layer on top of one.

  • Mobile PWA (install-ready)
  • Digital factory floor signage
  • Full audit trail (21 CFR Part 11)
  • Electronic signatures (Annex 11)
  • Role-based access control
  • Microsoft Entra SSO
  • Siloed SaaS deployment
  • Validated backups (verified daily)
  • ERP integration (M1/SAP/Plex)
  • Power BI bidirectional
  • OneDrive document linking
  • Self-service environment provisioning
app.mesvantage.com / admin / audit-trail

Audit Trail · 21 CFR Part 11

Immutable · Hash-chained · Exportable to FDA-ready PDF

3,482 events today ● Hash chain valid
Timestamp (UTC)
Actor
Action
Entity
Change
Hash
2026-05-07 14:06:18
Walsh F.
SIGN
DHR · SN-A4729-00184
Lock + e-signature
0x9A4F…E218
2026-05-07 14:06:14
Walsh F.
AUTH
DHR · SN-A4729-00184
Re-auth (≤3 min)
0x7B3C…0091
2026-05-07 13:58:42
auto
INGEST
CMM · HX-2026-1184
Parsed 18 features
0x4D8E…AA21
2026-05-07 13:42:11
Patel R.
CREATE
NCR · NCR-1147
Coolant Δ flagged
0x2F61…99A4
2026-05-07 13:30:55
Smith K.
UPDATE
WO · WO-4892
Op 020 → in-progress
0x8C19…F127
2026-05-07 13:22:09
Smith K.
AUTH
WO · WO-4892
Op start auth
0x6E40…4F09
2026-05-07 12:58:33
auto
EXPORT
Lot release · LT-2026-Q2-018
Sent to OEM portal
0x1A92…7C3D
2026-05-07 12:45:14
Walsh F.
SIGN
CAPA · CAPA-0089
QA approval signature
0x5B70…2E18
Hash-chain verified: latest block 0xE921…4A78 · prev 0xC4D3…81FB Export FDA-ready PDF →

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